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Maeda Lab at University of Wisconsin-Madison studies evolutionary diversification of core metabolic pathways (i.e. primary metabolism) in various plants through chemical, biochemical, genetic, and evolutionary analyses. Utilizing the acquired basic knowledge, we further aim to optimize plant metabolic network and improve chemical compositions of agricultural and bioenergy crops, such as for improved food nutrition, plant-based bioenergy and pharmaceutical production. read more Lab News NEW *2020 April Kaan Koper joined us from Thomas Okita lab at Washington State University. NEW *2020 April Bailey Kleven joined us from Jean-Michel Ané lab at UW-Madison. Welcome! 2020 January Beth Moore joined us from Michigan State University, Shin-Han Shiu Lab. 2020 January Tadhg Young joined our lab as a graduate student. Welcome! 2019 December Hiroshi's JBC review is now published here. 2019 November Jorge El-Azaz joined us from Francisco Cánovas' lab at the University of Málaga, Spain. 2019 September Our DOE BER grant has been funded! We will collaborate with Berkeley National Lab, Univ Potsdam, Univ Hokkaido, and JGI to construct nitrogen metabolic network of Arabidopsis and Sorghum. 2019 July Our NSF PGRP grant has been funded! We will investigate evolutionary history of tyrosine-derived lignin pathways in grasses to understand how unique primary metabolic network evolves in macroevolutionary scale. May 2019 Yusen's senior thesis has been selected for the 2019 Skoog and Curtis Scholarship from the UW Botany Department. Congratulations and good luck for your graduate study! April 2019 Caroline has been awarded a Hilldale Undergraduate Research Fellowship from the UW-Madison! March 2019 Our former graduate student, Craig has been selected for the recipient of 2019 Eric E. Conn Young Investigator Award from the American Society of Plant Biologists (ASPB). Congrats! December 2018 Minmin's and Kyoko's paper on in vivo characterization of Arabidopsis tyrosine aminotransferase mutants is now published in JBC December 2018 Samuel's paper on fungi TyrA characterization has been published at ABB. November 2018 Marcos's paper on in planta characterization of tyra2 mutant and BvTyrAa overexpressors are now published in Plant J! February 2018 Craig's review article on plant tyrosine metabolism has been published in Phytochemistry! November 2017 Microbial TyrA paper by Craig and Yusen is published in Frontiers Mol. Biosci.! October 2017 Samuel's beet story is now on NY Times and BBC (Spanish). October 2017 Samuel received the best oral presentation award of biochemistry at the 2017 SACNAS meeting. Congrats! September 2017 Samuel's paper on coordinated evolution of tyrosine and betalain biosynthetic pathways in Caryophyllales, in collaboration with Ya Yang (Univ. Michigan, now at Univ. Minnesota) and Sam Brockington (Cambridge), has been published at New Phytologist! Also, see UW News. June 2017 Craig's paper on structure-function analyses of legume PDH enzyme, in collaboration with Joe Jez lab, is now published in Nature Chem. Biol.! Also, see UW News. May 2017 Minmin's paper on yellow/red beets, in collaboration with Irwin Goldman's lab, is published in J. Agri. Food. Chem.! April 2017 Ryo Yokoyama is joining our lab as a JSPS postdoc fellow from Kyoto University. Welcome! September 2016 - Minmin's paper on tyrosine aminotransferases was accepted to Phytochemistry! August 2016 - Hiroshi and Maeda Lab received TWO awards, the Arthur Neish Young Investigator Award and the Elsevier Phytochemistry Young Investigator Award, at the PSNA meeting! August 2016 - Craig and Hiroshi both gave a talk at the PSNA meeting at UC Davis. July 2016 - Samuel gave a talk and Hiroshi chaired "Metabolic Diversity" mini-symposium at the ASPB meeting at Austin, Texas. May 2016 - Matt and Adi both received The Hilldale Undergraduate Research Fellowships from the Chancellor Rebecca Blank. Congratulations! November 2015 - We welcomed a new postdoc, Marcos Oliveira from Texas A&M, Dr. Ping He's lab. July 2015 - Craig received the best graduate oral presentation award at Gordon Research Seminar on Plant Metabolic Engineering and was selected for the chair of 2017 GRS on PME! March 2015 - Our USDA grant to elucidate and engineer tyrosine biosynthetic pathways in table beet has been awarded! January 2015 - Craig's paper was featured on the Cover of the January issue of Nature Chem. Biol.! November 2014 - Craig's work on identification of legume PDH enzymes has been published in Nature Chem. Biol.! Read more. September 2014 - We welcomed a new postdoc, Minmin Wang, who recently obtained PhD at UC Davis working with Dr. Florence Zakharov. August 2014 - Our NSF grant to investigate the diversification of plant tyrosine biosynthetic pathways has been awarded! July 2014 - Our study on the evolution of plant phenylalanine biosynthesis has been published in The Plant Cell! See the paper and UW news release. July 2014 - Hiroshi and Craig both gave a Mini-Symposium talk and Samuel presented a poster during the ASPB annual meeting at Portland OR. June 2014 - Hiroshi gave a talk at the Banff Conference on Plant Metabolism. January 2014 - Three manuscripts have been accepted or published! See the updated publication list. October 2013 - Hiroshi gave an invited talk, entitled "Molecular Evolution of the plant phenylalanine and tyrosine biosynthesis", at the 13th International Congress on Amino Acids, Peptides and Proteins (ICAPP, Galveston, Texas). July 2013 - Craig and Hiroshi presented posters at the Gordon Research Conference on Plant Metabolic Engineering (Waterville Valley, NH). May 2013 - Jacob graduated UW Madison and will start a graduate school at the Biochemistry Department, University of Iowa. Congratulations and good luck with your grad study! May 2013 - Julian moved to Chile, working as a research scientist at the Plant Biotechnology Centre of University Andres Bello. We will miss you! April 2013 - Maeda Lab presented PigmentArt during the 2013 Science Expedition at UW Madison. (see pictures) March 2013 - Craig and Samuel presented their work on Tyr biosynthesis at the Midwest Section Meeting of ASPB at Chicago State University. March 2013 - Samuel received the NSF Graduate Research Fellowship - Congratulations! February 2013 - Kyoko returned to the National Institute of Crop Science, Japan, after staying with us for one year. Good luck with your work in Japan! August 2012 - Julian joined the lab as a research scientist from USDA. Welcome to Maeda Lab! June 2012 - Samuel and Craig joined the lab from New Mexico and Ohio as Botany Ph.D. students. Welcome to Madison! see their pictures May 2012 - The review article, "The Shikimate Pathway and Aromatic Amino Acid Biosynthesis in Plants", was published in Annual Review of Plant Biology. April 2012 - Hiroshi presented a plenary lecture at the International Conference on Plant Chemical Biology, Jealott's Hill, UK. February 2012 - Kyoko joined the lab as a visiting scientist from the National Institute of Crop Science, Japan. Welcome to the US! Maeda Lab is starting in the Fall 2011 at the Department of Botany, Univ of Wisconsin-Madison. If you are interested in studying plant metabolism and physiology in the lab, please contact me at maeda2@wisc.edu. Hiroshi organized the 2011 Gordon Research Seminar on Plant Metabolic Engineering, which brings together junior scientists in the field of plant metabolism and aims to build a strong community to overcome various challenges in the discipline. Download the GRS flyer. Maeda Lab Contact University of Wisconsin, Madison Department of Botany 430 Lincoln Drive, Madison, WI 53706 USA (Google Map) Birge Hall room B214, +1-608-262-4288 (Lab) B217, +1-608-262-5833 (PI office) Email: maeda2@wisc.edu Web: https://botany.wisc.edu/staff/maeda-hiroshi-a/